<b>Vascular Smooth Muscle Cell Proliferation is Effectively Suppressed by the Non-specific Growth Factor Inhibitor Suramin</b>
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چکیده
منابع مشابه
Vascular smooth muscle cell proliferation is effectively suppressed by the non-specific growth factor inhibitor suramin.
The purpose of this study was to investigate the effects of the non-specific growth factor inhibitor suramin on smooth muscle cell proliferation in vitro and in vivo. Cultured vascular smooth muscle cells (VSMC) were stimulated by platelet-derived growth factor (PDGF) and cellular DNA synthesis assessed by [3H]-thymidine uptake. Suramin dose-dependently inhibited DNA synthesis in VSMC, and 100 ...
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ژورنال
عنوان ژورنال: Japanese Heart Journal
سال: 2001
ISSN: 0021-4868,1348-673X
DOI: 10.1536/jhj.42.221